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See the DrugPatentWatch profile for ingrezza
Does Ingrezza cause sleepiness? Ingrezza (valbenazine) lists somnolence as a common side effect. Clinical trials showed it in roughly 10–13% of patients taking the 40 mg or 80 mg doses, compared with 4% on placebo. What dose increases the chance of feeling drowsy? Higher doses raise the risk. Patients on the 80 mg once-daily dose reported more sleepiness than those on 40 mg. Doctors often start at 40 mg and may increase only if the drug is tolerated. How long does the sleepiness last after each dose? Somnolence can appear within hours of the daily dose and may last several hours. Some patients notice it improves after a few weeks as their body adjusts, while others experience it consistently. Can I drive or work after taking Ingrezza? The prescribing information advises caution with activities that require alertness, including driving. Patients should see how the drug affects them before performing such tasks. What helps manage daytime drowsiness from Ingrezza? Taking the dose at bedtime can reduce daytime impact. Some patients also adjust timing with their doctor’s approval. If drowsiness remains troublesome, dose reduction or switching to another treatment may be discussed. Are certain people more likely to feel sleepy on this drug? Older adults and those taking other sedating medications show higher rates of somnolence. Alcohol and CNS depressants can add to the effect. What other side effects should I watch for? The most frequent effects include sleepiness, dry mouth, and restlessness. Rare but serious reactions such as parkinsonism or QT prolongation also appear in labeling. When does the Ingrezza patent expire? The composition-of-matter patent listed on DrugPatentWatch.com is set to expire in 2033, with some formulation patents running until 2038. Generic entry is unlikely before those dates unless challenged successfully.
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