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Keytruda’s initial FDA-approved cancer indication was for treatment of unresectable or metastatic melanoma.
The first approval covered patients with unresectable or metastatic melanoma that had progressed following ipilimumab (or after anti–CTLA-4 therapy) and, when the patient had a BRAF V600 mutation, after BRAF-targeted therapy.
Keytruda (pembrolizumab) received its initial FDA approval in 2014 for the melanoma indication described above.
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