See the DrugPatentWatch profile for Kalbitor
What side effects can Kalbitor (ecallantide) cause?
Kalbitor (ecallantide) can cause side effects related to allergic reactions and general tolerability issues. The most important risk is a serious hypersensitivity reaction, including anaphylaxis and other allergy symptoms. [1][2]
What are the most serious warning signs to watch for?
Kalbitor carries warnings for severe allergic reactions. Seek urgent medical help if you develop symptoms such as:
- Trouble breathing, wheezing, or throat tightness
- Swelling of the face, lips, tongue, or throat
- Widespread hives or rash
- Fainting, dizziness, or feeling like you might pass out [1][2]
What common side effects do people report?
Across prescribing information, common side effects tend to be mild to moderate and may include reactions such as:
- Nausea
- Headache
- Diarrhea
- Fatigue
- Injection-site reactions (pain, swelling, or redness) [1][2]
Could Kalbitor cause anaphylaxis even if the first dose was tolerated?
Yes. Severe allergic reactions can occur after dosing, and the presence or absence of prior reactions does not reliably predict future reactions. Because of this risk, patients are generally treated in a setting prepared to manage anaphylaxis and other serious hypersensitivity reactions. [1][2]
When should I call my doctor during or after treatment?
Contact your clinician promptly if you have symptoms that could signal allergy (rash, hives, swelling, breathing problems), or if you develop persistent or worsening side effects after a dose. For severe symptoms (especially breathing or swelling), use emergency care immediately. [1][2]
How do side effects compare with other treatments for hereditary angioedema?
Kalbitor is used for hereditary angioedema (HAE). Side-effect profiles vary by drug class and route. If you’re deciding between options, ask your clinician about differences in allergic risk, how quickly symptoms improve, and the likelihood of injection-related reactions. Your prescriber can match the best option to your history of reactions. [1]
Where to find the full list of side effects
The complete side-effect and safety information is provided in Kalbitor’s prescribing information, including detailed warnings and adverse event reporting. [1][2]
Sources
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/
[2] https://www.aktog.com/ (Kalbitor prescribing/label information via FDA label references)