Promethazine hydrochloride (the active ingredient in the antihistamine/anti‑emetic drug promethazine) is sold both as a brand name and as a generic. Because it’s a prescription medication in most markets, the price you’ll see can vary a lot depending on:
| Factor | Typical impact on price |
|--------|------------------------|
| Country / region | Prices in the U.S., Canada, Europe, and Asia can differ by an order of magnitude. |
| Form & dosage | 25 mg tablets, 50 mg tablets, syrups (5 mg/mL), injectable vials – each has its own cost. |
| Quantity | A bottle of 30 tablets is usually cheaper per‑tablet than a single‑dose bottle. |
| Brand vs generic | The brand‑name version (e.g., Phenergan®) can be 2–4× pricier than the generic. |
| Insurance / pharmacy benefit | Many U.S. plans cover a portion or the entire cost; copay levels vary widely. |
| Specialty pharmacies | Some compounding or specialty outlets add a markup. |
Rough price ranges (U.S. as a reference)
| Form (generic) | Approx. cost for a 30‑tablet bottle | Per‑tablet cost |
|----------------|-------------------------------------|-----------------|
| 25 mg tablets | $5–$12 | $0.17–$0.40 |
| 50 mg tablets | $7–$15 | $0.23–$0.50 |
| 5 mg/mL oral syrup (60 mL bottle) | $10–$18 | $0.17–$0.30 per mL |
Brand‑name (Phenergan®) is usually 2–3× higher: 30 tablets might run $15–$35.
How to find the exact price
1. Check with your local pharmacy or hospital pharmacy – they can give you the current list price and any available discount programs.
2. Use online price‑comparison tools – in the U.S., GoodRx, Blink Health, or RxSaver will show you the lowest price at participating pharmacies.
3. Ask your prescribing clinician or pharmacist – they often have access to bulk pricing or manufacturer coupons.
4. Look at international price‑watch sites – Medscape’s “Drug Pricing” or the European Medicines Agency (EMA) databases can give a sense of European pricing.
If you let me know the exact dosage form, strength, and the country where you’re looking to purchase, I can give a more precise estimate.