When combining Advil (ibuprofen) and antacids, there can be potential interactions to be aware of. Ibuprofen belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), which can irritate the stomach lining and, in some cases, lead to stomach ulcers or acid reflux [1]. Antacids are used to neutralize stomach acid and relieve symptoms of acid reflux and heartburn [2].

The interaction between Advil and antacids occurs due to the altered gastric pH caused by antacids. Antacids can increase the gastric pH, which may reduce the absorption of ibuprofen and decrease its effectiveness [3]. However, this interaction is unlikely to cause severe side effects in most individuals.

It is important to note that long-term use of NSAIDs like Advil can lead to more severe side effects, including stomach ulcers, gastrointestinal bleeding, and kidney damage [1]. Combining NSAIDs with antacids may help alleviate gastrointestinal symptoms, but it does not eliminate the risk of these potential side effects [3].

In summary, combining Advil and antacids can reduce the absorption of ibuprofen, potentially decreasing its effectiveness. However, this interaction is unlikely to cause severe side effects in most individuals. It is essential to consult a healthcare professional or pharmacist for personalized advice regarding medication combinations [1][2][3].

Sources:

1. U.S. National Library of Medicine. (2021). Ibuprofen. MedlinePlus. <https://medlineplus.gov/druginfo/meds/a682035.html>
2. U.S. National Library of Medicine. (2021). Antacids. MedlinePlus. <https://medlineplus.gov/antacids.html>
3. DrugPatentWatch. (2021). Ibuprofen and Antacids: Interactions, Side Effects, and Dosage. DrugPatentWatch. <https://drugpatentwatch.com/ibuprofen-and-antacids-interactions-side-effects-and-dosage/>