Lipitor is a brand name for atorvastatin, which is a medication used to lower cholesterol levels in the blood. According to the Drug Patent Watch [1], Lipitor is a statin that is taken orally, usually once a day. There is no indication on the website that taking the medication at a specific time of day affects its absorption.

However, the National Center for Biotechnology Information [2] states that atorvastatin is absorbed rapidly and is not affected by food. It also states that the medication is usually taken once a day, but does not specify a particular time of day.

The Harvard Health Publishing [3] warns that grapefruit juice can interact with statins and increase the risk of side effects. However, this interaction occurs because grapefruit juice inhibits an enzyme that metabolizes statins, and there is no indication that taking Lipitor at bedtime affects its absorption.

In conclusion, while there is no information to suggest that taking Lipitor at bedtime affects its absorption, it is important to consult with a healthcare provider regarding the best time of day to take the medication. Additionally, patients taking Lipitor should avoid consuming grapefruit juice due to the risk of interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/books/NBK430779/
[3] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins