Alirocumab (Praluent®) – Rough Price Snapshot (United States, 2024)
| Item | Typical Range (USD) |
|------|---------------------|
| List price per 150 mg vial | $1,400 – $2,000 (average $1,700) |
| Cost per 75 mg vial | $700 – $1,000 (average $850) |
| Average monthly out‑of‑pocket cost (with insurance) | $200 – $700 (depends on deductible, co‑pay, and plan type) |
| Average monthly cost for uninsured patients | $2,000 – $4,000 (typical dosing 75 mg every 2 weeks or 150 mg monthly) |
How the cost breaks down
1. Dosing regimens
- 75 mg every 2 weeks (2 vials per month) → ~US$2,800 – $4,000/month (list price)
- 150 mg every month (1 vial per month) → ~US$1,400 – $2,000/month (list price)
2. Insurance impact
- Most commercial plans cover alirocumab with a co‑pay or co‑insurance of 5 – 10 % of the list price.
- Many Medicare Part D plans include alirocumab, but patients may face a formulary “step‑in” or prior‑authorization requirement that can delay coverage.
3. Patient assistance
- Amgen Patient Assistance Program (PAP): Offers free medication to qualifying low‑income patients who meet income and insurance criteria.
- Prescription discount cards: Some pharmacy benefit managers provide a 20 – 30 % discount on the list price for patients paying out of pocket.
How to verify current pricing
- Manufacturer’s website – Amgen posts the latest wholesale acquisition cost (WAC) and average retail price.
- FDA’s “Drugs@FDA” database – Lists approved dosing, strength, and label price.
- Pharmacy benefit manager (PBM) or pharmacy app – Show real‑time cost based on your insurance.
---
Quick Takeaway
While the list price of alirocumab can run $1,400 – $2,000 per vial, most patients pay considerably less thanks to insurance, discount programs, or manufacturer assistance. Uninsured patients should explore the Amgen PAP and pharmacy discount cards to reduce out‑of‑pocket costs.
If you’re looking for pricing in a specific country or under a particular insurance plan, let me know and I can dig into those details for you!