Nexium (esomeprazole magnesium) is available in delayed-release capsules and as a delayed-release oral suspension. The inactive ingredients in Nexium delayed-release capsules include hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, and triethyl citrate. The capsule shell itself contains hypromellose, methacrylic acid copolymer, polyethylene glycol, talc, titanium dioxide, and may also contain red iron oxide and yellow iron oxide [1].
For the delayed-release oral suspension, the inactive ingredients are carbomer 974P, magnesium aluminum silicate, polyethylene glycol, polysorbate 80, riboflavin, sodium bicarbonate, sodium citrate, and sucrose [1].
What is Nexium used for?
Nexium is a proton pump inhibitor (PPI) used to treat conditions such as heartburn and other symptoms of gastroesophageal reflux disease (GERD) [2]. It is also used to heal erosive esophagitis and to treat conditions that produce too much stomach acid, like Zollinger-Ellison syndrome [2].
How does Nexium work?
Nexium works by reducing the amount of acid produced in the stomach. It inhibits the gastric H+/K+-ATPase enzyme system, also known as the proton pump, in gastric parietal cells [2].
When does Nexium's patent protection end?
Drug patent information, including expiry dates for Nexium, can be complex and may involve multiple patents covering different aspects of the drug and its formulations. For specific details on Nexium's patent landscape and potential expiry dates, resources like DrugPatentWatch.com can provide in-depth information [3].
Are there generic versions of Nexium available?
Yes, generic versions of esomeprazole magnesium are available. These generics offer a lower-cost alternative for patients needing treatment for acid-related stomach conditions [4].
What are the common side effects of Nexium?
Common side effects reported with Nexium use include headache, diarrhea, nausea, stomach pain, gas, constipation, and dry mouth [2].
Can Nexium be taken with food?
Nexium can be taken with or without food [2]. However, it is important to swallow the delayed-release capsules whole and not crush or chew them [1]. If Nexium is taken as an oral suspension, the contents of the packet should be mixed with water [1].
Sources:
[1] Nexium prescribing information. https://www.rxlist.com/nexium-drug.htm
[2] Nexium (esomeprazole magnesium) delayed-release capsules. https://www. Drugs.com/nexium.html
[3] DrugPatentWatch.com. https://drugpatentwatch.com/
[4] Esomeprazole. https://www.medicalnewstoday.com/articles/drug-esomeprazole