What are the side effects of Zytiga?

Reported Side Effects of Zytiga

Zytiga (abiraterone) is a prescription medication used to treat certain types of prostate cancer. Like any medication, it can have side effects. According to the FDA [1] and clinical studies, common side effects of Zytiga include:

* Fatigue: Feeling weak or tired is a common side effect of Zytiga. This can be due to the medication's impact on hormone levels.
* Hypertestosterone: Zytiga can increase testosterone levels in the body, which can lead to symptoms like acne, hair loss, and increased libido.
* Edema: Swelling in the legs, ankles, and feet is a possible side effect of Zytiga.
* Diarrhea: Abdominal pain and diarrhea are common gastrointestinal side effects of Zytiga.
* Urinary Tract Infections: Zytiga can increase the risk of urinary tract infections, including kidney stones.

Other potential side effects of Zytiga include:
* Hypertension: Zytiga can cause high blood pressure in some patients.
* Cardiovascular events: There is a risk of cardiovascular events, such as heart attacks and strokes, in patients taking Zytiga.
* Hyperkalemia: Abiraterone can increase potassium levels in the body, which can lead to heart problems and muscle weakness.
* Osteoporosis: Zytiga can increase the risk of osteoporosis and fractures, particularly in patients taking glucocorticoids.

Patient Concerns and Clinical Data

Clinical trials have shown that Zytiga is effective in treating certain types of prostate cancer [2]. However, patients should discuss their individual risks and benefits with their doctor, especially if they have pre-existing medical conditions or take other medications.

Zytiga is manufactured by Janssen Oncology, and its patent expired in 2019 [3]. This has led to the development of generic versions and biosimilars, which can offer cost savings for patients and payers.

When to Consult a Doctor

If you are taking Zytiga and experience any of the following, contact your doctor immediately:

* Severe side effects, such as vomiting or difficulty breathing.
* Symptoms of a urinary tract infection, such as burning during urination or increased frequency.
* Changes in heart rate or blood pressure.
* Muscle weakness or spasms.
* Fatigue or weakness that interferes with daily activities.

Additional Information

Zytiga is not approved for use in women or children. Pregnant or breastfeeding women should not take Zytiga. To minimize side effects, patients should follow their doctor's instructions and take the medication as directed.

Sources:

[1] FDA – Zytiga (Abiraterone Acetate)

[2] J Clin Oncol. 2011 Jun 10;29(17):2341-8.

[3] DrugPatentWatch.com – Zytiga (Abiraterone Acetate) patent information