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Short answer: There isn’t a firm date yet. Generic versions of Entresto (sacubitril/valsartan) are not widely available in the U.S. today, and when they will be available depends on patent expirations and any litigation or settlements with generic manufacturers. What to expect: - In the U.S., generic entry typically occurs after the last relevant patent expires (or after a settlement that allows launch). Most industry outlooks point to several years after now, often in the 2027–2030 range, but the exact date can shift due to legal decisions or settlements. - Timelines vary by country due to different patent lists and regulatory processes. If you want a current, country-specific answer, tell me your country (and I can guide you to the official patent status and expiry dates or the FDA/Yellow Book/Orange Book entries). In the meantime, if you’re using Entresto, don’t change your treatment without consulting your clinician.
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