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Can patients with liver disease use Lipitor? Patients with liver disease need caution when considering Lipitor. The drug is contraindicated in active liver disease or unexplained persistent elevations of liver enzymes. Doctors usually monitor liver function closely in patients with a history of liver disease. How does Lipitor affect liver function tests? Lipitor can raise liver enzymes such as ALT and ALT in some patients. Many cases stay asymptomatic and resolve when treatment stops. Persistent or marked elevations require stopping the drug. Clinical trials show rates of enzyme elevation remain under 3 percent. What happens if patients continue Lipitor after enzyme elevations? Patients who keep taking the drug after significant liver enzyme rises may develop rare cases of liver injury. Monitoring helps detect changes early. Most elevations reverse after discontinuation. Rare cases of liver failure have occurred, but they remain uncommon. When does Lipitor's patent expire? Lipitor's patent expired in 2011. Since then, atorvastatin, the generic form, has entered the market widely. Generic versions cost far less than the brand-name drug.
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