Crinone (intravaginal progesterone) is a fairly common hormone therapy used mainly for fertility treatment and for luteal‑phase support. Because it’s sold as a prescription medication, the price you’ll see depends on a few key factors:
| Factor | How it affects cost |
|--------|---------------------|
| Dosage | A 5 mg gel contains 500 mg of progesterone; a 10 mg gel contains 1 000 mg. Most U.S. regimens start with 5 mg once daily and may increase to 10 mg. The higher the dose, the more you pay per month. |
| Formulation | Crinone comes in a single‑dose tube (usually 5 mg) or a 28‑dose pack (5 mg each). A pack of 28 5 mg tubes is typically the most convenient and cost‑effective for a 28‑day course. |
| Insurance | If you have insurance that covers hormonal fertility medications, the out‑of‑pocket cost can be a small copay (often $10–$50). Without coverage, the full retail price applies. |
| Pharmacy/Location | Prices can vary 10–30 % between chain pharmacies, independent drugstores, and online retailers. Some pharmacies offer “generic” or “brand‑equivalent” progesterone gel that may be cheaper. |
Rough U.S. retail range (before insurance)
| Dose | Approx. price for 28‑day supply |
|------|---------------------------------|
| 5 mg (28 tubes) | $30–$70 |
| 10 mg (28 tubes) | $60–$120 |
These estimates come from a snapshot of major U.S. pharmacy websites and national drug‑price databases (e.g., GoodRx, Healthgrades, or the U.S. Federal Drug Price Database). The actual price can be slightly higher or lower depending on your pharmacy, any available coupons, or manufacturer discount programs.
Tips to get the best price
1. Check with your provider – Some fertility clinics have bulk‑purchase agreements that reduce cost for patients.
2. Ask about manufacturer coupons – The manufacturer of Crinone occasionally offers free or discounted tubes to qualifying patients.
3. Compare pharmacies – Use online price‑comparison tools (e.g., GoodRx, RxSaver) to see which local pharmacy offers the lowest price.
4. Consider insurance – If you have a health plan that covers fertility medications, call your insurer’s pharmacy benefits manager to confirm coverage and copay amounts.
Bottom line
If you’re paying out of pocket, expect roughly $30–$70 for a 28‑day supply of the standard 5 mg Crinone gel and $60–$120 for the higher 10 mg dose. With insurance, the cost can drop dramatically, often to a small copay. Always double‑check the most current price at your chosen pharmacy, as prices can change quickly.