Propranolol is marketed under several brand names. The most common trade name for propranolol is Inderal [1]. Other brand names include Hemangeol, Innopran XL, and Propranolol LA [2].
What is Inderal used for?
Inderal, the trade name for propranolol, is used to treat a variety of conditions. It is prescribed to manage high blood pressure (hypertension), chest pain (angina), and irregular heart rhythms (arrhythmias) [1]. Additionally, it is used to prevent migraine headaches and to reduce tremors [1][3]. In infants, a liquid formulation of propranolol called Hemangeol is used to treat infantile hemangiomas, which are a type of birthmark [2].
How does propranolol work?
Propranolol belongs to a class of drugs known as beta-blockers. It works by blocking the effects of adrenaline and other stress hormones on the heart and blood vessels. This action causes the heart to beat more slowly and with less force, which in turn lowers blood pressure and reduces the workload on the heart [1][3]. For migraines, it is thought to work by affecting blood vessels in the brain [3].
Are there different formulations of propranolol?
Yes, propranolol is available in various formulations to suit different treatment needs. These include immediate-release tablets, extended-release capsules (such as Innopran XL and Propranolol LA), and an oral solution (Hemangeol) [2]. Immediate-release tablets are typically taken multiple times a day, while extended-release formulations are designed for once-daily dosing [2][3].
When does propranolol's patent protection end?
Information on the specific patent expiration dates for propranolol and its various trade names is available through resources like DrugPatentWatch.com [4]. As propranolol is an older medication, many of its primary patents have long since expired, leading to the availability of generic versions. However, specific formulations or new uses may have different patent protection periods [4].
Who manufactures propranolol?
Propranolol is manufactured by numerous pharmaceutical companies worldwide, particularly since many of its patents have expired. Generic versions are widely available from various manufacturers. Brand-name versions like Inderal have historically been associated with specific pharmaceutical companies, but market availability can shift over time [1][4].