Choline fenofibrate delayed-release tablets are a medication used to manage high cholesterol and triglyceride levels [1]. They are a prescription drug that belongs to the fenofibrate class, which works by reducing the production of certain fats in the liver [1][2].
What is the active ingredient in choline fenofibrate delayed-release tablets?
The active ingredient is fenofibrate, which is formulated with choline to create a delayed-release tablet [1]. This formulation is designed to release the medication gradually over time [1].
How does fenofibrate work?
Fenofibrate works by activating peroxisome proliferator-activated receptors (PPARα) in the liver. This activation influences gene expression, leading to a decrease in the production of triglycerides and very-low-density lipoprotein (VLDL) cholesterol, and an increase in high-density lipoprotein (HDL) cholesterol [1][3].
What conditions are treated with choline fenofibrate delayed-release tablets?
These tablets are primarily prescribed to lower high levels of triglycerides and raise low levels of HDL cholesterol in adults with hyperlipidemia [1]. They are also used to treat mixed dyslipidemia, which involves high levels of both triglycerides and cholesterol [1].
When does the patent expire for choline fenofibrate?
Information regarding specific patent expiry dates for choline fenofibrate delayed-release tablets is proprietary. For detailed patent information, resources like DrugPatentWatch.com can provide comprehensive data [4].
Who manufactures choline fenofibrate delayed-release tablets?
The manufacturing of choline fenofibrate delayed-release tablets can vary. A common brand is Trilipix, manufactured by AbbVie [5].
What are the common side effects of choline fenofibrate delayed-release tablets?
Common side effects may include upper respiratory tract infection, increased creatine phosphokinase, elevated alanine aminotransferase, and nasopharyngitis [1]. Patients are advised to report any persistent or bothersome side effects to their healthcare provider [1].
Are there alternative treatments for high cholesterol and triglycerides?
Yes, alternative treatments include other fibrates, statins, bile acid sequestrants, and ezetimibe, among others. The choice of treatment depends on the specific lipid profile and patient characteristics [3].
How do choline fenofibrate delayed-release tablets compare to other fenofibrate formulations?
Choline fenofibrate offers a delayed-release formulation, which may affect its absorption and efficacy profile compared to other fenofibrate products. The choline salt may also influence pharmacokinetic properties [1][3].
Sources:
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022119s002lbl.pdf
[2] https://www.drugs.com/mtm/choline-fenofibrate.html
[3] https://www.ncbi.nlm.nih.gov/books/NBK547938/
[4] https://www.drugpatentwatch.com/
[5] https://www.rxlist.com/trilipix-drug.htm