How much did lipitor lower cholesterol initially?

How much did Lipitor (atorvastatin) lower cholesterol in early clinical results?

In early studies of Lipitor, patients had substantial reductions in cholesterol levels soon after starting treatment. For example, in one commonly cited trial, atorvastatin reduced LDL cholesterol by about 39% versus placebo at around 16 weeks of treatment [1].

How soon were cholesterol reductions seen?

Cholesterol reductions began early in treatment, with decreases in LDL and total cholesterol observed within the first several weeks, and larger average reductions typically building over the first few months of therapy [1].

What cholesterol measure are people usually asking about—LDL or total?

When people ask “How much did Lipitor lower cholesterol initially,” they usually mean LDL cholesterol reduction (the standard primary target statin measure). The same studies also reported decreases in total cholesterol and other lipid fractions, but LDL is the figure most often highlighted in “initial” results [1].

Sources:
[1] https://www.drugpatentwatch.com/