How does pregabalin affect heart rate?
Pregabalin can change heart rate in some people. Reported effects include palpitations and, in some cases, faster heart rate (tachycardia). These reactions are part of the drug’s potential side effects, even though pregabalin is not primarily classified as a heart-rate drug.[1]
What heart symptoms should you watch for while taking pregabalin?
People taking pregabalin may report symptoms such as:
- Palpitations (a noticeable, sometimes fast heartbeat)
- Feeling lightheaded or unwell along with heart racing
- Chest discomfort if heart symptoms are severe
If pregabalin causes a marked increase in heart rate, new irregular rhythms, fainting, or chest pain, that’s a reason to get urgent medical care rather than adjusting dosing on your own.[1]
Is a higher heart rate a common pregabalin side effect?
Heart-rate–related complaints (like palpitations/tachycardia) are possible but are not necessarily the most common pregabalin effects for everyone. Frequency varies by patient and dose, and it can also depend on other medications and conditions.[1]
Could other meds or conditions make pregabalin’s heart-rate effects worse?
Yes. Heart rate can be influenced by:
- Other drugs that affect circulation or rhythm
- Substances such as alcohol or stimulants
- Underlying heart disease, anxiety, dehydration, thyroid problems, or infection
If you’re experiencing pregabalin-associated palpitations, clinicians often look for these contributing factors too.[1]
When should you contact a clinician or stop pregabalin?
Contact a clinician promptly if you have new or worsening palpitations, persistent tachycardia, fainting, or chest pain. Stopping pregabalin suddenly can cause withdrawal-type symptoms in some patients, so decisions about stopping or lowering the dose should generally be guided by a prescriber.[1]
Pregabalin brand vs. generic—does heart-rate risk change?
The active ingredient is the same (pregabalin) whether the product is brand-name or generic, so the potential for side effects like palpitations/tachycardia should be similar. Differences between products are more about formulation and dosing consistency than the core side-effect profile.[1]
Source
[1] FDA prescribing information (pregabalin) — adverse reactions including palpitations/tachycardia. https://www.accessdata.fda.gov/scripts/cder/daf/