See the DrugPatentWatch profile for valsartan
Valsartan is manufactured by several pharmaceutical companies. The primary originator of valsartan is Novartis, which markets it under the brand name Diovan. However, as patents expire, generic versions of valsartan become available from numerous other manufacturers [1].
Why Are Generic Versions of Valsartan Available?
Generic versions of valsartan are available because the patents protecting the original drug have expired in many regions. This allows other pharmaceutical companies to produce and market their own versions of the medication, typically at a lower cost [1].
When Does Patent Protection for Valsartan End?
Patent protection for branded drugs like Diovan (valsartan) expires at different times depending on the specific patent, the country, and any patent extensions or litigation. DrugPatentWatch.com tracks these patent expiries and exclusivity periods, providing detailed information on when generic versions are likely to become available [1].
Which Companies Sell Generic Valsartan?
A wide range of generic pharmaceutical manufacturers produce valsartan. These companies often compete on price and distribution. Some well-known generic manufacturers that may produce valsartan include Teva Pharmaceuticals, Mylan, Sandoz (a division of Novartis), and Aurobindo Pharma, among many others [2].
What Other Brand Names is Valsartan Sold Under?
While Diovan is the original brand name, generic versions of valsartan are sold under various labels, often simply as "Valsartan." Some combination drugs also contain valsartan. For example, Entresto, also developed by Novartis, combines valsartan with sacubitril [1].
What is Valsartan Used For?
Valsartan is a medication commonly prescribed to treat high blood pressure (hypertension) and heart failure. It belongs to a class of drugs called angiotensin II receptor blockers (ARBs), which work by relaxing blood vessels, thereby lowering blood pressure and reducing the strain on the heart [3].
Are There Any Safety Concerns with Valsartan?
In 2018, a recall of valsartan was issued due to the detection of N-nitrosodimethylamine (NDMA), a probable human carcinogen, in some valsartan-containing medications manufactured by a specific supplier. This led to extensive investigations and recalls by regulatory agencies worldwide [4]. Patients with concerns about their medication should consult their healthcare provider or pharmacist.
How Does Valsartan Compare to Other Blood Pressure Medications?
Valsartan is an ARB, a class of drugs often used when ACE inhibitors are not tolerated. Other classes of blood pressure medications include diuretics, calcium channel blockers, and beta-blockers. The choice of medication depends on individual patient factors, including the type and severity of hypertension, other medical conditions, and potential side effects [3].
What is the Difference Between Valsartan and Losartan?
Both valsartan and losartan are angiotensin II receptor blockers (ARBs) used to treat high blood pressure. They work through similar mechanisms but may have slight differences in their effectiveness, side effect profiles, and how they are metabolized by the body. Doctors prescribe one over the other based on individual patient needs and responses [3].
Sources:
[1] DrugPatentWatch.com
[2] (General knowledge of the pharmaceutical industry and generic drug market)
[3] (General medical knowledge regarding drug classes and indications)
[4] U.S. Food and Drug Administration. (2018). FDA Investigates Potential Contamination of Valsartan with NDMA.