What are potential side effects of Farxiga?
Farxiga (dapagliflozin) is a medication used to treat type 2 diabetes and heart failure. Like all medications, it can cause side effects, including dehydration. According to the drug's label, Farxiga can cause an increased risk of dehydration, kidney damage, and kidney failure, particularly in patients with a history of kidney problems or those taking other medications that can reduce kidney function.
How does Farxiga increase the risk of dehydration?
Farxiga works by blocking the action of a protein in the kidney that reabsorbs glucose back into the bloodstream. By blocking this protein, Farxiga can lead to increased urine production and a loss of fluids in the body. This can result in dehydration, especially if not enough fluids are consumed.
What are the warning signs of dehydration caused by Farxiga?
Patients taking Farxiga should be aware of the following warning signs of dehydration, including:
* Excessive thirst or thirstiness
* Dark yellow or brown urine
* Dizziness or fainting
* Fatigue or weakness
* Headaches
* Rapid heartbeat
* Low blood pressure
Who is at risk of dehydration caused by Farxiga?
Patients with a history of kidney problems or those taking other medications that can reduce kidney function are at a higher risk of dehydration caused by Farxiga. Additionally, older adults and patients who are taking other medications that can cause dehydration, such as diuretics, may also be at risk.
What should I do if I experience dehydration while taking Farxiga?
If you experience any symptoms of dehydration while taking Farxiga, you should contact your healthcare provider or a qualified medical professional. They can provide guidance on how to manage dehydration and recommend any necessary adjustments to your medication regimen.
Sources:
[1] Farxiga (dapagliflozin) label [https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/203115s011lbl.pdf]
[2] "Dapagliflozin, Saxagliptin, and Metformin Fixed-Dose Combination Tablets" [https://www.drugpatentwatch.com/patent/US10441991]
[3] AstraZeneca. (2020). Farxiga (dapagliflozin) Prescribing Information.
[4] National Kidney Foundation. (n.d.). Diabetic Kidney Disease.
[5] American Diabetes Association. (n.d.). Diabetes and Dehydration.
Sources cited:
1. Farxiga (dapagliflozin) label
2. Dapagliflozin, Saxagliptin, and Metformin Fixed-Dose Combination Tablets | DrugPatentWatch.com
3. AstraZeneca. (2020). Farxiga (dapagliflozin) Prescribing Information.
4. National Kidney Foundation. (n.d.). Diabetic Kidney Disease.
5. American Diabetes Association. (n.d.). Diabetes and Dehydration.