Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the body. It belongs to a class of drugs called statins and works by inhibiting an enzyme involved in the production of cholesterol in the liver [2].

While Lipitor does not directly affect the absorption of dietary fat, it indirectly reduces the absorption of cholesterol from the intestine [3]. The drug reduces the amount of low-density lipoprotein (LDL) cholesterol in the bloodstream, which is commonly known as "bad" cholesterol. By doing so, Lipitor reduces the amount of cholesterol that is available for absorption from the intestine, leading to a decrease in the overall absorption of cholesterol [3].

A study published in the Journal of Clinical Pharmacology found that atorvastatin had no significant effect on the absorption of dietary fat in healthy individuals [1]. However, another study published in the Journal of Lipid Research suggested that atorvastatin may decrease the absorption of dietary fat in individuals with high cholesterol levels [3].

It is important to note that Lipitor should be taken with food, as it is better absorbed in the presence of dietary fat [2]. Additionally, individuals taking Lipitor should follow a healthy diet and exercise regularly to achieve optimal cholesterol-lowering effects [2].

In conclusion, Lipitor indirectly reduces the absorption of cholesterol from the intestine, but it does not have a significant effect on the absorption of dietary fat. It is important to take Lipitor with food and follow a healthy lifestyle to achieve optimal cholesterol-lowering effects.

Sources:
[1] https://pubmed.ncbi.nlm.nih.gov/18631412/
[2] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[3] https://www.ncbi.nlm.nih.gov/books/NBK430779/