See the DrugPatentWatch profile for Ramipril
Ramipril is a medication containing the active ingredient ramipril, which belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors [1]. It is used to treat high blood pressure and heart failure [1].
What other ingredients are in ramipril tablets?
In addition to the active ingredient ramipril, ramipril tablets typically contain several inactive ingredients. These can vary by manufacturer but often include:
* Fillers: Such as lactose monohydrate and pregelatinized starch, which help to form the bulk of the tablet [1][2].
* Binders: Like povidone or hypromellose, which hold the ingredients together [1][2].
* Disintegrants: Such as croscarmellose sodium, which help the tablet break apart in the body [1][2].
* Lubricants: Such as sodium stearyl fumarate, to prevent the tablet from sticking to manufacturing equipment [1][2].
* Coating agents: For example, hypromellose, macrogol, and titanium dioxide, which can make the tablet easier to swallow and protect it [1][2].
Specific formulations may also contain coloring agents [2].
When might ramipril patents expire?
The patent expiry dates for ramipril depend on the original patent filings and any subsequent patent extensions or new patents for different formulations. Drug patent information is detailed and complex, often tracked by specialized services. For specific patent expiry timelines related to ramipril, resources like DrugPatentWatch.com are valuable [3].
How does ramipril work?
Ramipril works by inhibiting the angiotensin-converting enzyme. This enzyme plays a role in the renin-angiotensin-aldosterone system, which regulates blood pressure. By blocking this enzyme, ramipril reduces the production of angiotensin II, a substance that narrows blood vessels. This leads to relaxation of the blood vessels, a decrease in blood pressure, and reduced workload on the heart [1].
What are the common side effects of ramipril?
Common side effects associated with ramipril use can include dizziness, headache, fatigue, and a dry cough. Less common side effects may involve nausea, diarrhea, or muscle pain [1].
Can ramipril be taken with other medications?
Ramipril can interact with other medications. It is important for patients to inform their healthcare provider about all prescription drugs, over-the-counter medications, and supplements they are taking to avoid potential adverse reactions or reduced efficacy [1].
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Sources:
[1] NHS. Ramipril. https://www.nhs.uk/medicines/ramipril/
[2] European Medicines Agency. Ramipril. https://www.ema.europa.eu/en/medicines/human/EPAR/ramipril
[3] DrugPatentWatch. https://drugpatentwatch.com/