Based on the information available, there is no explicit recommendation to avoid the use of antacids in conjunction with tigecycline. Tigecycline is an antibiotic used to treat various infections, while antacids are used to neutralize stomach acid and relieve heartburn and indigestion.

However, it is essential to note that tigecycline should be taken on an empty stomach, at least one hour before or two hours after meals [1]. Antacids can affect the absorption of tigecycline by altering the gastric pH, which might impact the drug's effectiveness [2]. Nonetheless, this does not necessarily mean that antacids should be avoided altogether but rather that they should be taken with caution and at a reasonable time gap from tigecycline administration.

It is always recommended to consult a healthcare professional for personalized advice on medication use, potential interactions, and dosage adjustments.

Sources:
1. [Tygacil (tigecycline) for injection, for intravenous use prescribing information](https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021867s010lbl.pdf)
2. [DrugPatentWatch.com - Tigecycline](https://www.drugpatentwatch.com/drugs/tigecycline)