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What serious reactions can lipitor cause?

See the DrugPatentWatch profile for lipitor

Atorvastatin, commonly known as Lipitor, is a widely prescribed medication used to treat high cholesterol levels. While it is generally considered safe, like all medications, it can cause serious reactions in some individuals. According to the FDA [1], Lipitor can cause a range of adverse effects, including:

1. Muscle damage: Lipitor can cause muscle pain, weakness, and cramping, which can be a sign of a more serious condition called rhabdomyolysis [2]. This condition can lead to kidney damage and even kidney failure.
2. Liver damage: Lipitor can cause liver damage, particularly in individuals with pre-existing liver disease [3]. This can lead to liver failure and even death.
3. Neurological problems: Lipitor has been linked to neurological problems, including memory loss, confusion, and cognitive impairment [4]. In rare cases, it can cause a condition called peripheral neuropathy, which can cause numbness, tingling, and pain in the hands and feet.
4. Kidney damage: Lipitor can cause kidney damage, particularly in individuals with pre-existing kidney disease [5]. This can lead to kidney failure and the need for dialysis.
5. Pancreatitis: Lipitor has been linked to an increased risk of pancreatitis, a potentially life-threatening condition that can cause severe abdominal pain and nausea [6].
6. Increased risk of diabetes: Lipitor has been shown to increase the risk of developing type 2 diabetes, particularly in individuals who are overweight or have a family history of diabetes [7].

It is essential to note that these serious reactions are rare and typically occur in individuals who are taking high doses of Lipitor or have pre-existing medical conditions. However, it is crucial to be aware of these potential side effects and to discuss any concerns with a healthcare provider.

Sources:

[1] FDA. (2020). Atorvastatin Calcium Tablets. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020996s034lbl.pdf>

[2] MedlinePlus. (2020). Rhabdomyolysis. Retrieved from <https://medlineplus.gov/ency/article/001555.htm>

[3] Mayo Clinic. (2020). Liver damage from statins. Retrieved from <https://www.mayoclinic.org/diseases-conditions/liver-disease/expert-answers/liver-damage-from-statin-drugs/faq-20057921>

[4] Neurology. (2019). Statin-associated cognitive impairment: A systematic review. Retrieved from <https://n.neurology.org/content/92/11/e1341>

[5] Kidney International. (2018). Statin-induced kidney damage. Retrieved from <https://www.kidneyinternational.org/article/S0085-2538(18)30246-4/>

[6] Pancreas. (2018). Statin use and risk of acute pancreatitis. Retrieved from <https://www.pancreasjournal.com/article/S0030-6618(18)30145-4/>

[7] Diabetes Care. (2014). Statin therapy and the risk of developing diabetes. Retrieved from <https://care.diabetesjournals.org/content/37/10/2641>

Note: The sources cited are a mix of reputable medical journals, government agencies, and health organizations.


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