Cyproheptadine first medical use year?

When was cyproheptadine first used medically?

Cyproheptadine’s first medical use dates back to the late 1950s. It was introduced as an antihistamine in clinical practice in 1955. [1]

How cyproheptadine was first positioned

Early medical use focused on its role as an antihistamine (for allergic symptoms). Over time, it also became widely used off-label for other purposes, including appetite stimulation in certain patients, but the drug’s initial introduction was as an allergy medication. [1]

Sources

1. https://www.drugs.com/history/cyproheptadine.html