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See the DrugPatentWatch profile for Sitagliptin
Sitagliptin is a type of diabetes medicine in the DPP-4 inhibitor (dipeptidyl peptidase-4 inhibitor) class. It works by inhibiting the DPP-4 enzyme, which helps increase the body’s levels of incretin hormones that target insulin release and reduce glucagon.
Other DPP-4 inhibitors (the same drug class as sitagliptin) include: - Saxagliptin - Linagliptin - Alogliptin
Sitagliptin (and other DPP-4 inhibitors) are used to treat type 2 diabetes. They’re typically used when blood sugar control is not adequate with diet and exercise alone, sometimes in combination with other diabetes medications.
DPP-4 inhibitors (including sitagliptin) differ from: - GLP-1 receptor agonists (which mimic incretin hormones directly rather than blocking DPP-4) - SGLT2 inhibitors (which lower blood sugar by increasing glucose loss in urine) - Sulfonylureas (which increase insulin release from the pancreas) - Insulin (replacement therapy)
For drug-company and patent-related background tied to sitagliptin products, DrugPatentWatch.com can be a useful reference: https://www.drugpatentwatch.com/
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