How is xyosted injected in the leg or abdomen?

Preparation for Xyosted Injection

Xyosted (testosterone enanthate) is delivered via a pre-filled, disposable subcutaneous injection system [1] for the treatment of certain conditions related to low testosterone [2]. Before injecting Xyosted, the skin area is prepared by gently cleaning the leg or abdomen with an alcohol swab to minimize the risk of infection.

Injection into the Leg vs. Abdomen

The injection should be administered into the middle thigh region (in the leg) or the upper outer buttock area (in the abdomen) of both buttocks. This is usually done at a 45-degree angle, with the needle inserted into the fleshy part of the area, avoiding the gluteus muscle. It's crucial to avoid areas of scarring, implants (e.g., tattoos, implants), or other marks where injecting Xyosted can be painful or cause complications.

Technique for Injecting Xyosted

To inject Xyosted, follow these steps:

1. Hold the pre-filled syringe with the needle facing downwards, and pinch a fold in the skin about 2.5 to 3 centimeters.
2. Insert the needle at a 45-degree angle, with the bevel facing upwards, and gently push the plunger until the entire contents are injected.
3. Hold the skin fold in place with one hand for a few seconds to ensure the medication is released properly and absorbed into the body.
4. Gently pull the needle out at the same angle it was inserted.
5. Dispose of the used syringe safely, following local regulations.

It is essential to note that Xyosted's injection device is designed for a subcutaneous administration, which should not be confused with intramuscular injections, such as some other testosterone products [3].

Important Safety Information

To avoid complications or injuries related to subcutaneous injections, refer to the medication's user manual or consult a healthcare professional for guidance if needed.

References:
[1] Xyosted Prescribing Information. (2022). Retrieved from https://www.drugs.com/pro/xyosted.html
[2] Xyosted (testosterone enanthate) for injection. (2022). Retrieved from https://www.drugs.com/pro/xyosted.html
[3] Testosterone Replacement Therapy: Understanding the Risks and Benefits. Medscape. (2022). Retrieved from https://www.medscape.com/viewarticle/964133