Aspirin and Advil are both nonsteroidal anti-inflammatory drugs (NSAIDs) that are used to treat pain, fever, and inflammation. Aspirin is a salicylate drug that works by inhibiting the production of prostaglandins, which are chemicals that cause pain and inflammation. Advil, on the other hand, is a brand name for ibuprofen, which works by blocking the production of prostaglandins as well.

While both aspirin and Advil are used to treat similar conditions, they have different mechanisms of action and can interact with each other. Taking both aspirin and Advil together can increase the risk of side effects, such as stomach ulcers, bleeding, and kidney damage.

According to the FDA [2], taking aspirin and Advil together can decrease the effectiveness of aspirin in preventing heart attacks and strokes. This is because Advil can interfere with the antiplatelet effects of aspirin, which means that aspirin may not be able to prevent blood clots as effectively.

It is important to note that while aspirin and Advil can interact with each other, they can also interact with other medications and medical conditions. It is always important to talk to a healthcare provider before taking any new medications or changing your medication regimen.

In conclusion, aspirin and Advil are both NSAIDs that can be used to treat pain, fever, and inflammation. However, taking them together can increase the risk of side effects and decrease the effectiveness of aspirin in preventing heart attacks and strokes. It is important to talk to a healthcare provider before taking any new medications or changing your medication regimen.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] https://www.fda.gov/media/76636/download
[3] https://www.healthline.com/health/pain-relief/aspirin-ibuprofen