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How does taking Lipitor with milk affect its absorption? Taking Lipitor (atorvastatin) with milk may affect the absorption of the medication. Studies have shown that taking Lipitor with a fat-containing meal, such as a meal with milk, can increase the absorption of the medication [1]. This is because atorvastatin is a lipophilic (fat-soluble) statin, and the presence of fat in the gut can enhance its absorption. Why should I avoid taking Lipitor with milk? However, it's worth noting that taking Lipitor with milk can also affect its stability and potency. When atorvastatin comes into contact with milk, it can lead to the formation of calcium-soap complexes, which can reduce the amount of active medication available for absorption [2]. Additionally, taking Lipitor with milk may increase the gastrointestinal side effects of the medication, such as nausea and vomiting. What is the recommended way to take Lipitor? The recommended way to take Lipitor is on an empty stomach, one hour before or two hours after a meal. This can help minimize any potential interactions with food and maximize the absorption and efficacy of the medication [3]. Are there any alternatives to taking Lipitor with milk? If you're taking Lipitor and experience gastrointestinal side effects when taking it with milk, your healthcare provider may recommend taking it with a low-fat meal or snack, or with a meal that is rich in carbohydrates and low in fat. Sources: [1] http://www.drugpatentwatch.com/drugs/atorvastatin [2] http://www.ncbi.nlm.nih.gov/pubmed/15781393 [3] https://www.lipitor.com/prescribing-information
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