Ticagrelor brilinta tablet 90 mg?

Ticagrelor (brand name Brilinta) 90 mg tablets are an antiplatelet medicine used to reduce the risk of heart attack, stroke, and cardiovascular death in people with acute coronary syndromes (like NSTEMI/STEMI) and in certain patients after a heart attack or coronary intervention. It is always used with low-dose aspirin.

Key points about Ticagrelor 90 mg:
- How it works: It blocks the P2Y12 receptor on platelets, reducing platelet aggregation and the chance of clot formation.
- Typical dosing (ACS or post-PCI):
- Loading dose: 180 mg (two 90 mg tablets) at start.
- Maintenance: 90 mg twice daily for up to 12 months.
- After 12 months, if continued therapy is appropriate, the dose may be reduced to 60 mg twice daily.
- Aspirin dose should generally be low (around 81–100 mg daily).
- When not to use (contraindications):
- Active or serious bleeding.
- History of intracranial hemorrhage.
- Severe hepatic impairment.
- Known allergy to ticagrelor.
- Cautions and interactions:
- Bleeding risk is higher; monitor for unusual bleeding or bruising.
- Caution in liver disease; severe liver disease is a contraindication.
- Do not use with high-dose aspirin (>100 mg daily) because it can reduce ticagrelor’s effectiveness.
- Avoid strong CYP3A4 inhibitors (e.g., certain antifungals like ketoconazole, some HIV drugs like ritonavir) and strong inducers (e.g., rifampin) because they change ticagrelor levels.
- Other antiplatelet or anticoagulants increase bleeding risk; use under physician supervision.
- Common side effects:
- Bleeding (gums, nosebleeds, easy bruising)
- Shortness of breath (dyspnea)
- Headache, dizziness
- Nausea or flushing
- Missed dose: If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double up.
- Pregnancy and breastfeeding: Seek medical advice; use only if clearly needed and prescribed.
- Practical tips:
- Take exactly as prescribed with or without food, but try to take at similar times each day.
- Avoid NSAIDs that raise bleeding risk unless advised by your doctor.
- Tell all healthcare providers you are taking ticagrelor before any surgery or dental work.

If you’re taking Brilinta 90 mg or considering it, talk with your doctor about your specific condition, kidney/liver function, other medications, and how long you should stay on the 90 mg dose versus switching to 60 mg. If you notice unusual or heavy bleeding, chest pain, severe shortness of breath, or signs of an allergic reaction, seek medical care promptly.