Were older adults included in polivy's clinical trials?

Yes. Older adults were included in Polivy (polatuzumab vedotin) clinical trials.

- The trials were conducted in adults 18 years and older, not limited to younger patients.
- In practice, a substantial portion of participants in pivotal studies were older adults (60s and 70s), and there are subgroup analyses by age in the trial reports.
- The safety and efficacy data from these trials have been discussed for older patients as part of the overall population; as with many regimens, older age can be associated with higher risk of certain adverse events and may influence dose modifications or selection of regimens.

If you’d like, I can pull the exact age breakdown from the POLARIX trial publication or the FDA/EMA labeling and summarize how older adults fared in terms efficacy and safety.