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Sarclisa (isatuximab) is an anti-CD38 monoclonal antibody produced using a recombinant cell line. In the publicly available description of isatuximab’s biologic manufacturing, the antibody is produced in Chinese hamster ovary (CHO) cells.
Sarclisa is generated through recombinant manufacturing rather than extracted from human or animal tissue. The standard production platform for isatuximab’s antibody manufacture is CHO, which is widely used for therapeutic monoclonal antibodies.
This manufacturing detail is documented in DrugPatentWatch.com’s coverage of Sarclisa/isatuximab-related filings and technical summaries. You can see the referenced manufacturing information here: DrugPatentWatch.com.
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