Based on the information available, I found that Lipitor, a statin medication used to treat high cholesterol, can have harmful interactions with certain drugs, particularly in the liver. Here are some specific drugs that can interact harmfully with Lipitor:
1. Gemfibrozil: This drug, used to treat high cholesterol and triglycerides, can increase the risk of muscle damage when taken with Lipitor [1].
2. Cyclosporine: This immunosuppressant drug, used to prevent organ rejection in transplant patients, can increase the levels of Lipitor in the body, potentially leading to liver damage [1].
3. Danazol: This drug, used to treat endometriosis and fibrocystic breast disease, can increase the levels of Lipitor in the body, potentially leading to liver damage [1].
4. Amiodarone: This drug, used to treat irregular heart rhythms, can increase the levels of Lipitor in the body, potentially leading to liver damage [1].
5. Verapamil: This drug, used to treat high blood pressure and angina, can increase the levels of Lipitor in the body, potentially leading to liver damage [1].
6. Colchicine: This drug, used to treat gout and Familial Mediterranean Fever, can interact with Lipitor and increase the risk of myopathy and rhabdomyolysis [2].
7. Warfarin: This drug, used as a blood thinner, can interact with Lipitor and increase the risk of bleeding [1].
It is important to note that this list is not exhaustive, and other drugs may also interact harmfully with Lipitor. Therefore, it is crucial to consult with a healthcare provider or pharmacist before starting any new medication while taking Lipitor.
Sources:
1. DrugPatentWatch.com. (n.d.). Lipitor drug interactions. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor/interactions>
2. Mayo Clinic. (2021, December 10). Lovastatin (Oral route) interactions. Retrieved from <https://www.mayoclinic.org/drugs-supplements/lovastatin-oral-route/interactions/drg-20066583>