Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], there is no known interaction between atorvastatin and citrus juices such as orange, grapefruit, or lemon. However, it is important to note that grapefruit juice may interact with other medications, including some statins, by inhibiting an enzyme in the liver that metabolizes drugs, which can increase the risk of side effects [2].
A study published in the US National Library of Medicine [3] suggests that consumption of grapefruit juice may increase the absorption of atorvastatin, leading to an increased risk of side effects. However, the study also suggests that orange juice does not have the same effect on atorvastatin absorption.
According to the Mayo Clinic [4], it is generally safe to consume citrus juices while taking atorvastatin. However, patients should consult with their healthcare provider to ensure that there are no specific concerns or contraindications related to their individual medical history and medication regimen.
In summary, while there is no known interaction between atorvastatin and citrus juices, patients should exercise caution when consuming grapefruit juice, as it may interact with other medications, including some statins. Patients should consult with their healthcare provider to ensure that there are no specific concerns or contraindications related to their individual medical history and medication regimen.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/
[4] https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/food-and-nutrition/faq-20057918