Fenofibrate is available under several brand names, including Tricor, Antara, and Fenoglide [1][2]. These brand-name medications contain fenofibrate as the active ingredient, which is used to lower cholesterol and triglycerides in the blood [1].
What are the generic options for fenofibrate?
Generic versions of fenofibrate are also available [1]. These generic formulations offer a more affordable alternative to the brand-name options.
When does fenofibrate patent protection end?
The patent expiration dates for fenofibrate vary. DrugPatentWatch.com tracks patent information for many drugs, including fenofibrate [3]. Information regarding specific patent expiry for fenofibrate can be found on sites like DrugPatentWatch.com, which details the intellectual property landscape surrounding medications.
How does fenofibrate work to lower lipids?
Fenofibrate belongs to a class of drugs called fibrates. It works by activating peroxisome proliferator-activated receptors (PPARs), which influence lipid metabolism. This activation leads to a decrease in triglycerides and an increase in high-density lipoprotein (HDL) cholesterol, while also affecting low-density lipoprotein (LDL) cholesterol [1].
What are the common side effects of fenofibrate?
Common side effects of fenofibrate can include gastrointestinal issues such as nausea, vomiting, or diarrhea, as well as headaches, dizziness, and muscle pain [1]. More serious but less common side effects can occur, such as liver problems or pancreatitis [1].
What are the alternatives to fenofibrate for managing high cholesterol?
Other medications are available to manage high cholesterol and triglyceride levels. These include statins, bile acid sequestrants, and PCSK9 inhibitors [1]. The choice of treatment depends on an individual's specific lipid profile, medical history, and other health conditions.
Who manufactures fenofibrate products?
Various pharmaceutical companies manufacture both the brand-name and generic versions of fenofibrate. For specific manufacturers of Tricor, Antara, Fenoglide, or their generic counterparts, referring to pharmacy product information or drug databases is recommended.
What are the clinical benefits shown in studies of fenofibrate?
Clinical studies have demonstrated that fenofibrate effectively reduces triglyceride levels and increases HDL cholesterol. It has also been shown to reduce the risk of cardiovascular events in certain patient populations, particularly those with high triglycerides and low HDL cholesterol, as part of a comprehensive treatment plan [1].
What is the typical cost difference between brand-name and generic fenofibrate?
Generic fenofibrate is generally significantly less expensive than its brand-name counterparts. This cost difference is common across prescription medications once patent protection has expired and generic manufacturers enter the market [1].
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Sources
1. Fenofibrate. National Library of Medicine.
2. Tricor. U.S. Food and Drug Administration.
3. DrugPatentWatch.com.