Lipitor is a medication that is used to lower cholesterol levels in the body. It is a type of medication called a statin, which works by blocking the production of cholesterol in the liver [1]. Grapefruit juice has been known to interact with certain medications, including some statins, which can affect their absorption and metabolism in the body [2].

According to the Harvard Health Publishing, grapefruit juice can increase the level of Lipitor in the bloodstream, leading to an increased risk of side effects. This is because grapefruit juice contains compounds that can inhibit the enzymes responsible for breaking down Lipitor in the body. As a result, the medication may stay in the bloodstream for longer periods, increasing the risk of side effects such as muscle pain and liver damage [2].

The NHS also confirms that grapefruit juice can interact with Lipitor, and advises patients to avoid consuming grapefruit or grapefruit juice while taking the medication. They recommend that patients speak to their doctor or pharmacist if they have any concerns about their medication and its interactions with grapefruit juice [3].

In conclusion, Lipitor absorption can be affected by grapefruit juice. Grapefruit juice contains compounds that can inhibit the enzymes responsible for breaking down Lipitor in the body, leading to an increased risk of side effects. Patients taking Lipitor should avoid consuming grapefruit or grapefruit juice while taking the medication, and speak to their doctor or pharmacist if they have any concerns about their medication and its interactions with grapefruit juice [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[3] https://www.nhs.uk/common-health-questions/medicines/does-grapefruit-affect-my-medicine/