Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. According to the Advil website [2], it is safe to take Advil with food or on an empty stomach, but taking it with food may help reduce the risk of stomach upset. However, Healthline [3] advises taking ibuprofen with food or milk to avoid stomach irritation, especially if you have a history of gastrointestinal problems. It is important to follow the dosage instructions on the label or as directed by your doctor and not to exceed the recommended dose. Also, it is essential to inform your doctor or pharmacist about any medical conditions you have or medications you are taking to avoid any potential drug interactions. In summary, taking Advil with food is safe, and it may help reduce the risk of stomach upset, but it is advisable to take it with food or milk to avoid stomach irritation, especially if you have a history of gastrointestinal problems.

Sources:
[2] https://www.advil.com/faqs-en/advil-pain/
[3] https://www.healthline.com/health/ibuprofen-on-empty-stomach