Strides Pharma Science has been involved in the manufacturing and supply of minocycline hydrochloride [1]. The company's product is used for various indications, including the treatment of moderate to severe acne vulgaris, as well as other bacterial infections [1].
What indications is minocycline hydrochloride used for?
Minocycline hydrochloride is primarily indicated for the treatment of inflammatory lesions of moderate to severe acne vulgaris [1]. It is also used to treat infections caused by susceptible bacteria, such as respiratory tract infections, urinary tract infections, skin infections, and venereal diseases [1].
How does minocycline hydrochloride work?
Minocycline hydrochloride is a tetracycline-class antibiotic. It works by inhibiting bacterial protein synthesis, which is essential for bacterial growth and reproduction [1]. This bacteriostatic action ultimately leads to the death of susceptible bacteria [1].
What is the regulatory status of Strides Pharma's minocycline hydrochloride?
Strides Pharma has obtained approvals for its minocycline hydrochloride products in various markets. For instance, the company has received tentative approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for minocycline hydrochloride extended-release tablets [2].
When does patent exclusivity expire for minocycline hydrochloride?
The patent exclusivity for minocycline hydrochloride has largely expired, as it is an older antibiotic [3]. However, specific formulations or extended-release versions might have separate patent protections. DrugPatentWatch.com provides detailed information on patent expiry dates for various drugs.
Are there alternative treatments for acne?
Yes, there are several alternative treatments for acne, including topical retinoids, benzoyl peroxide, salicylic acid, and other oral antibiotics [4]. For severe or persistent acne, hormonal therapies and isotretinoin are also options [4].
Who are the other manufacturers of minocycline hydrochloride?
Several pharmaceutical companies manufacture and supply minocycline hydrochloride, including other generic drug manufacturers [5]. The market for minocycline hydrochloride is competitive, with various companies offering both immediate-release and extended-release formulations [5].
What are the potential side effects of minocycline hydrochloride?
Common side effects of minocycline hydrochloride can include nausea, vomiting, diarrhea, dizziness, and skin sensitivity to sunlight [1]. More serious side effects, though less common, can involve liver problems, allergic reactions, and changes in blood counts [1].
Sources:
1. Strides Pharma Science Limited. (n.d.). Minocycline Hydrochloride. Retrieved from https://www.strides.com/pipeline/products/minocycline-hydrochloride/
2. Strides Pharma Science Limited. (2018, November 27). Strides Pharma Science announces Tentative Approval for Minocycline Hydrochloride Extended Release Tablets. Retrieved from https://www.strides.com/media/press-releases/2018/11/27/strides-pharma-science-announces-tentative-approval-for-minocycline-hydrochloride-extended-release-tablets/
3. DrugPatentWatch.com. (n.d.). Minocycline Hydrochloride Patents. Retrieved from https://drugpatentwatch.com/minocycline-hydrochloride
4. American Academy of Dermatology Association. (n.d.). Acne: Diagnosis and treatment. Retrieved from https://www.aad.org/public/diseases/acne/treatment
5. Drugs.com. (n.d.). Minocycline - Uses, Side Effects, Interactions - Drugs.com. Retrieved from https://www.drugs.com/drug-classes/tetracyclines.html