Is lybalvi an antipsychotic?

Is Lybalvi an antipsychotic?

Lybalvi is not itself described as a standalone antipsychotic. It is a combination medicine that contains olanzapine (an antipsychotic) plus samidorphan (an opioid antagonist), used for schizophrenia and also for bipolar I disorder. Because it includes olanzapine, Lybalvi contains an antipsychotic component. [1]

How does the “antipsychotic” part work with samidorphan?

Olanzapine is the drug in Lybalvi with antipsychotic effects. Samidorphan is added to affect opioid receptors, which is intended to help reduce certain olanzapine-related issues (the main focus is weight gain-related risk). The presence of samidorphan doesn’t change that Lybalvi still includes an antipsychotic drug (olanzapine). [1]

What conditions is Lybalvi used for?

Lybalvi is used in schizophrenia and bipolar I disorder, and those indications rely on olanzapine’s antipsychotic activity. [1]

Sources

[1] https://www.drugs.com/lybalvi.html