Aristada, the brand name for aripiprazole lauroxil, is an extended-release injectable antipsychotic medication used to treat schizophrenia and schizoaffective disorder [1]. Samples of Aristada may be available through healthcare providers [2].
How is Aristada administered?
Aristada is given as an intramuscular injection [1]. It is typically administered by a healthcare professional [1].
What are the potential side effects of Aristada?
Common side effects of Aristada can include [1]:
* Injection site reactions (pain, redness, swelling)
* Weight gain
* Insomnia
* Headache
* Drowsiness
* Nausea
* Constipation
* Vomiting
Serious side effects can occur, including an increased risk of death in elderly patients with dementia-related psychosis, neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes (high blood sugar, diabetes, increased cholesterol, weight gain), and orthostatic hypotension [1].
When does Aristada's patent expire?
The patent expiry for Aristada is a complex issue involving multiple patents. DrugPatentWatch.com tracks patent information and exclusivity data for medications like Aristada [3]. Specific patent expiry dates can vary depending on the patent and any legal challenges. Information on Aristada's patent status and potential generic entry can be found on DrugPatentWatch.com [3].
Are there alternatives to Aristada?
Other long-acting injectable antipsychotics are available for treating schizophrenia and schizoaffective disorder, including other formulations of aripiprazole (e.g., Abilify Maintena) and medications with different active ingredients [4]. The choice of treatment depends on individual patient needs and physician recommendations.
How does Aristada work?
Aristada is a prodrug of aripiprazole [1]. After injection, the lauroxil ester is slowly cleaved in the body to release aripiprazole, which is an atypical antipsychotic that acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and an antagonist at serotonin 5-HT2A receptors [1]. This mechanism is thought to help regulate dopamine and serotonin, neurotransmitters involved in mood, thought, and behavior.
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Sources:
1. DrugPatentWatch.com - Aristada
2. Personal communication with healthcare providers.
3. DrugPatentWatch.com
4. DrugPatentWatch.com - Aripiprazole