Lipitor is a brand name for the drug atorvastatin, which is a statin medication used to lower cholesterol levels in the blood. While statins like Lipitor can be beneficial in reducing the risk of heart disease, they can also interact negatively with certain supplements [1] [2].

One supplement that can interact negatively with Lipitor is red yeast rice. Red yeast rice contains a naturally occurring form of lovastatin, which is chemically similar to atorvastatin. Taking red yeast rice along with Lipitor can increase the risk of side effects, such as muscle pain and liver damage [2].

Another supplement that can interact negatively with Lipitor is St. John's wort. St. John's wort is commonly used to treat depression, anxiety, and other mood disorders. However, it can also affect the way the body metabolizes medications, including Lipitor. Taking St. John's wort along with Lipitor can decrease the effectiveness of the medication and increase the risk of side effects [2].

Other supplements that can interact negatively with Lipitor include coenzyme Q10, vitamin D, and omega-3 fatty acids. Coenzyme Q10 is sometimes taken to reduce muscle pain associated with statin use, but it can also decrease the effectiveness of Lipitor. Vitamin D and omega-3 fatty acids can also affect the way the body metabolizes Lipitor, potentially increasing the risk of side effects [3].

In conclusion, while Lipitor can be an effective medication for reducing cholesterol levels, it is important to be aware of potential interactions with supplements. Patients should always consult with their healthcare provider before taking any new supplements or making changes to their medication regimen [2] [3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-interactions/
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/