See the DrugPatentWatch profile for dovato
Dovato was approved by the U.S. Food and Drug Administration (FDA) on February 4, 2020 [1].
What is Dovato and what is it used for?
Dovato is a prescription medication used to treat human immunodeficiency virus type 1 (HIV-1) infection in adults and children weighing at least 33 pounds (15 kg) [2]. It is specifically indicated for patients who have no history of prior antiviral treatment for HIV-1 infection [2]. Dovato is a complete treatment regimen, meaning it contains two antiretroviral drugs in a single tablet [2].
How does Dovato work?
Dovato contains two active ingredients: dolutegravir and lamivudine [2]. Dolutegravir is an integrase strand transfer inhibitor (INSTI) that works by blocking the action of integrase, an enzyme that HIV needs to copy itself and multiply [3]. Lamivudine is a nucleoside analog reverse transcriptase inhibitor (NRTI) that works by blocking the action of reverse transcriptase, another enzyme that HIV needs to replicate [3]. By using two different types of drugs that work in different ways, Dovato helps to reduce the amount of HIV in the body, called the viral load [2].
What is the active ingredient in Dovato?
The active ingredients in Dovato are dolutegravir and lamivudine [2].
Who manufactures Dovato?
Dovato is manufactured by ViiV Healthcare [4].
Are there other HIV medications like Dovato?
Dovato is a single-tablet regimen containing two drugs. Other HIV treatment options may involve single-tablet regimens with different combinations of drugs or multiple pills taken separately [5]. The choice of HIV medication depends on individual patient factors, including viral load, resistance to certain drugs, and potential side effects [5].
When does the patent for Dovato expire?
Patent information for Dovato, including expiry dates, can be found on DrugPatentWatch.com [1]. DrugPatentWatch.com tracks patent expirations for pharmaceutical products, which is relevant for understanding when generic versions of a drug might become available.
What are the potential side effects of Dovato?
Common side effects of Dovato can include headache, diarrhea, nausea, insomnia, and fatigue [2]. Serious side effects are possible and may include allergic reactions, liver problems, and lactic acidosis [2]. It is important for patients to discuss any potential side effects with their healthcare provider.
Where can I find more information about Dovato?
More detailed information about Dovato, including prescribing information and clinical trial data, can be found through official FDA resources and the drug's manufacturer, ViiV Healthcare [1][2][4].
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**Sources
[1] https://drugpatentwatch.com
[2] https://www.hiv.gov/hiv-basics/treatment/taking-hiv-medication/dovato
[3] https://www.hhs.gov/programs/clinical-care/hiv-aids-guidelines/antiretroviral-therapy/index.html
[4] https://www.viivhealthcare.com
[5] https://www.aidsinfo.nih.gov/guidelines/guideline/detail/21/guidelines-for-the-use-of-antiretroviral-agents-in-adults-and-adolescents-living-with-hiv