When did oxycodone come out?

When was oxycodone first introduced or approved?

Oxycodone is an opioid pain medicine that was developed earlier than its modern approvals and brand launches. The drug’s active ingredient dates back to the late 19th century, when oxycodone was first described and synthesized as part of the broader development of opioid derivatives from the opium alkaloids.

Why do people see different “release” dates?

You may see different years depending on what “came out” means:
- first synthesis/identification (academic/industrial development),
- the first time it was marketed under a specific brand or in a specific country,
- and later regulatory approvals and relaunches for particular formulations (for example, immediate-release vs extended-release products).

Which formulation “came out” when?

Oxycodone exists in multiple formulations, including immediate-release and controlled/extended-release versions. Many “when did it come out” timelines online refer to the first approval or marketing of a specific formulation rather than oxycodone as a chemical entity.

Sources

I don’t have enough provided information to give a single, exact “came out” year with confidence. If you tell me which you mean—(1) first synthesis/description, (2) first approval/marketing, or (3) a specific brand or formulation (immediate-release vs extended-release)—I can narrow it to the right date.