Lacosamide is an antiepileptic drug that is used for the treatment of partial-onset seizures in adults and children over 4 years of age. It is available under the brand name Vimpat [3]. However, if lacosamide is not an appropriate treatment option or not well-tolerated, there are alternative medications available for maintenance therapy of partial-onset seizures.

One alternative medication for maintenance therapy is Levetiracetam, which is available under the brand name Keppra. Levetiracetam is a well-tolerated medication that has a favorable safety profile [2]. Another alternative medication is Topiramate, which is available under the brand name Topamax. Topiramate is also effective in treating partial-onset seizures and has been shown to be well-tolerated in clinical trials [2].

Additionally, there are other antiepileptic drugs available that can be used as alternatives to lacosamide for maintenance therapy. These include carbamazepine, oxcarbazepine, phenytoin, and valproate [2].

It is important to note that the choice of medication for maintenance therapy of partial-onset seizures depends on various factors, including the patient's medical history, age, and comorbidities. Therefore, it is essential to consult with a healthcare provider to determine the most appropriate treatment option.

Sources:
[1] DrugPatentWatch. Lacosamide. https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE. Accessed 13 July 2021.
[2] Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med. 2000;342(5):314-319. doi: 10.1056/NEJM200002033420503.
[3] Medscape. Lacosamide (Vimpat, MotPoly XR). https://reference.medscape.com/drug/vimpat-motpoly-xr-lacosamide-343026. Accessed 13 July 2021.