What side effects can Advil (ibuprofen) cause?
Advil’s active ingredient is ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID). Common side effects typically involve the stomach and intestines, and can include:[1]
- Stomach pain or burning (heartburn)
- Nausea
- Vomiting
- Gas or indigestion
- Diarrhea or constipation
- Dizziness or headache
What are the serious side effects to watch for?
Some ibuprofen side effects are signs of potentially dangerous problems and need urgent medical attention. These include:[1]
- Signs of an allergic reaction: hives, swelling of the face or throat, trouble breathing
- Serious stomach or intestinal bleeding: black or tarry stools, vomiting blood or material that looks like coffee grounds, severe or persistent stomach pain
- Kidney problems: unusual decrease in urine, swelling in the legs/ankles, unexplained fatigue
- Serious liver problems (less common): yellow skin/eyes, dark urine
- Chest pain, shortness of breath, weakness on one side of the body, or trouble speaking (possible cardiovascular or neurologic event)
How do the risks change with dose, age, and other meds?
Side-effect risk generally increases with higher doses and longer use. Your risk can also be higher if you:[1]
- Are older (especially if 65+)
- Take other NSAIDs at the same time (for example, naproxen or more ibuprofen)
- Have a history of ulcers or GI bleeding
- Have kidney disease
- Take blood thinners (like warfarin) or antiplatelet drugs
- Take corticosteroids, SSRIs/SNRIs, or other medicines that increase bleeding risk
When should someone stop Advil and get help?
Stop taking ibuprofen and seek medical care right away if you get:[1]
- Symptoms of a severe allergic reaction
- Signs of GI bleeding (black/tarry stools or vomiting blood)
- Severe abdominal pain that does not go away
- Signs of kidney trouble (major change in urination, significant swelling)
Are there alternatives if Advil doesn’t agree with you?
If Advil causes stomach problems or if you cannot take NSAIDs, people often ask about alternatives such as acetaminophen for pain/fever, but the best choice depends on your health conditions and the reason you’re taking it. Check with a clinician or pharmacist, especially if you have ulcer/bleeding risk, kidney disease, or heart disease.[1]
Does Advil have any long-term risks?
Long-term or frequent NSAID use can increase the chance of stomach bleeding and can also affect kidney function and blood pressure control. This is why the lowest effective dose for the shortest time is usually recommended.[1]
Sources:
1. https://www.drugs.com/sfx/ibuprofen-side-effects.html