The National Drug Code (NDC) 70518 identifies quetiapine, an atypical antipsychotic medication [1]. Quetiapine is used to treat conditions such as schizophrenia, bipolar disorder (manic and depressive episodes), and major depressive disorder, often as an add-on therapy [2][3]. It works by affecting the activity of certain natural substances in the brain [2].
What are the different formulations of quetiapine?
Quetiapine is available in immediate-release and extended-release formulations [4]. The extended-release version, often marketed as Seroquel XR, allows for once-daily dosing [4].
When does the patent for quetiapine expire?
The original patents for quetiapine have expired, allowing for the availability of generic versions [5]. DrugPatentWatch.com tracks patent expirations for medications, providing a resource for information on patent lifecycles [5].
Who manufactures generic quetiapine?
Multiple pharmaceutical companies manufacture generic quetiapine. These companies produce the drug after the original patents have lapsed, making it more affordable and accessible [5].
What are the common side effects of quetiapine?
Common side effects associated with quetiapine include drowsiness, dizziness, dry mouth, constipation, weight gain, and blurred vision [2][3]. More serious side effects can occur, such as movement disorders, changes in heart rhythm, and metabolic changes like increased blood sugar and cholesterol levels [2][3].
How does quetiapine compare to other antipsychotics?
Quetiapine is classified as an atypical antipsychotic, distinct from older, typical antipsychotics. Atypical antipsychotics generally have a lower risk of causing movement-related side effects but may carry a higher risk of metabolic side effects compared to typical agents [6]. Comparisons with other specific atypical antipsychotics like risperidone or olanzapine would depend on specific treatment goals and patient profiles [6].
What is the typical dosage and administration for quetiapine?
Dosage and administration of quetiapine vary depending on the condition being treated, the formulation (immediate-release or extended-release), and individual patient response [3]. Treatment often starts with a low dose and is gradually increased [3]. It can be taken with or without food, although taking it with food may reduce gastrointestinal upset [2].