Based on the information available, it is not recommended to combine Advil (ibuprofen) and tricyclic antidepressants without consulting a healthcare professional.

Tricyclic antidepressants (TCAs) are a class of medications used primarily to treat depression, but they are also used for other conditions such as anxiety disorders, chronic pain, and insomnia. They work by increasing the levels of certain neurotransmitters in the brain.

Advil, on the other hand, is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting the production of prostaglandins, which are hormone-like substances that cause pain and inflammation.

Combining Advil and TCAs can increase the risk of serious side effects, such as bleeding in the stomach and intestines, kidney damage, and liver damage. This is because both medications can affect the kidneys and the stomach lining, increasing the risk of these side effects when taken together.

It is important to note that this information is based on general guidelines and may not apply to all individuals. Therefore, it is always best to consult a healthcare professional before combining any medications, including Advil and TCAs.

Sources:

1. <https://www.drugs.com/drug-interactions/tricyclic-antidepressants-ibuprofen-463-175-572-1313.html>
2. <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/tricyclic-antidepressants/art-20049449>
3. <https://www.webmd.com/drugs/2/drug-16952-83/advil/ibuprofen-oral/details>
4. <https://www.drugpatentwatch.com/drugs/tricyclic-antidepressants>