Standard Starting Dose for Adults
Lipitor (atorvastatin calcium) typically starts at 10 mg or 20 mg once daily for adults with high cholesterol or cardiovascular risk. Doctors adjust based on LDL cholesterol levels, response, and factors like kidney function.[1][2]
Dosage by Condition
- High cholesterol (primary hyperlipidemia): Initial 10-20 mg daily; max 80 mg.
- Mixed dyslipidemia: Same as above.
- Homozygous familial hypercholesterolemia: Start 10-20 mg; often up to 80 mg.
- Post-heart attack or stroke prevention: 10-80 mg daily.
Take any time of day, with or without food. Swallow whole; don't split or crush.[1][2][3]
Dose Adjustments and Max Limits
Most patients reach goal on 10-20 mg. Increase every 2-4 weeks if needed, up to 80 mg max. Lower starting doses (5-10 mg) for those prone to muscle issues, on certain drugs like fibrates, or with liver impairment. Elderly patients often start lower due to higher side effect risk.[1][2]
What If You Miss a Dose or Overdose
Take missed dose as soon as remembered unless near next one—then skip. Never double up. Overdose symptoms include muscle pain or weakness; seek emergency care.[1][3]
Common Side Effects with Higher Doses
Muscle pain (5-10% of patients), especially above 40 mg, can signal rhabdomyolysis. Liver enzyme rises occur in 0.5-2%. Report unexplained pain or dark urine.[2][3]
Sources
[1]: Lipitor Prescribing Information (Pfizer)
[2]: Drugs.com - Lipitor Dosage
[3]: MedlinePlus - Atorvastatin