Does Xeljanz (tofacitinib) cause hair loss?
Yes. Hair loss (scalp hair thinning or shedding) is a reported side effect with Xeljanz (tofacitinib). If you notice new shedding, thinning patches, or worsening scalp hair loss after starting Xeljanz, it’s worth contacting your prescriber for guidance on whether to continue and how to evaluate other causes. [1]
What other side effects or causes can look like Xeljanz-related hair loss?
Hair loss can also come from the underlying inflammatory condition being treated, recent illness, stress, thyroid problems, iron or vitamin deficiencies, and medication changes. Your clinician may review labs and timing (when shedding started relative to Xeljanz) to distinguish medication-related effects from these common contributors. [1]
How soon after starting Xeljanz might hair loss happen?
Medication-related shedding often shows up weeks to a few months after a trigger. With Xeljanz, if hair loss begins after starting or increasing the dose, the timing can fit medication-associated shedding, but the exact onset can vary by person and by hair-growth cycle. [1]
Is Xeljanz hair loss reversible?
In many cases, drug-associated hair shedding improves after the trigger is addressed (for example, dose adjustment or stabilizing the underlying condition). The pace of regrowth depends on the cause and the length of time the shedding has been happening. A clinician can advise whether continuing Xeljanz is reasonable and what monitoring or supportive care to use. [1]
What should you do if you’re getting hair loss while on Xeljanz?
Talk to your prescriber promptly rather than stopping the drug on your own. They may:
- check whether the pattern fits medication-related shedding versus a different cause,
- review your dose and other meds,
- consider lab work (often thyroid and iron-related tests),
- suggest dermatology input or supportive hair-care steps. [1]
When to seek urgent care
Seek urgent medical care if hair loss comes with other symptoms that suggest a serious reaction (for example, severe rash, mouth sores, swelling, breathing problems) or signs of infection, since Xeljanz can affect immune function. [1]
Can dermatologists treat hair loss while you stay on Xeljanz?
Often yes. Many hair-loss approaches depend on the underlying mechanism (for example, telogen effluvium-style shedding versus androgenetic pattern thinning). A dermatologist can assess the pattern and, if appropriate, recommend treatments that don’t interfere with your need for Xeljanz. Coordinate any new treatments with your prescriber. [1]
Sources
- Xeljanz (tofacitinib) prescribing information (FDA). https://www.accessdata.fda.gov/scripts/cder/daf/