See the DrugPatentWatch profile for Gabapentin
Gabapentin is available under various brand names, with the most well-known being Neurontin [1]. Other brand names include Gralise and Horizant [1].
Who Makes Neurontin and Other Gabapentin Brands?
The original manufacturer of Neurontin was Parke-Davis, which later became part of Pfizer [2]. Currently, Pfizer continues to market Neurontin [1]. Gralise is manufactured by Horizon Therapeutics, and Horizant is also marketed by Horizon Therapeutics [1].
When Did Gabapentin Go Off-Patent?
Gabapentin was first approved by the U.S. Food and Drug Administration (FDA) in 1993 [3]. The patent for Neurontin expired in 2000, leading to the availability of generic versions [4].
Are There Generic Versions of Gabapentin Available?
Yes, following the patent expiry of Neurontin, numerous generic versions of gabapentin have become available [4]. These generics are manufactured by various pharmaceutical companies.
What Are the Approved Uses for Gabapentin Medications?
Neurontin is approved for treating seizures associated with epilepsy and for managing postherpetic neuralgia, a type of nerve pain that follows shingles [5]. Gralise is specifically indicated for managing postherpetic neuralgia [1]. Horizant is approved for treating restless legs syndrome and postherpetic neuralgia [1].
What Is the Difference Between Gabapentin and Other Nerve Pain Medications?
Gabapentin is an anticonvulsant medication that works by affecting chemicals and nerves in the body that are involved in causing seizures and some types of pain. While it is effective for certain conditions like epilepsy and nerve pain, other medications may be used for different types of pain or neurological conditions, each with distinct mechanisms of action and side effect profiles [5]. For instance, some pain medications target inflammation, while others work on opioid receptors.