Ketorolac is marketed under several brand names, with Toradol being the most widely recognized [1][2]. Other brand names for ketorolac include Acular, Toradol IM, Toradol IV, and Toradol SL [1].
What is ketorolac used for?
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for short-term management of moderate to moderately severe pain [3]. It is often prescribed post-operatively or for conditions requiring significant pain relief [3].
How does ketorolac work?
Ketorolac functions by inhibiting cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins [3]. Prostaglandins are chemicals in the body that contribute to inflammation, pain, and fever [3]. By blocking their production, ketorolac reduces these symptoms [3].
What is the difference between ketorolac and other NSAIDs?
While ketorolac shares the NSAID mechanism of action with drugs like ibuprofen or naproxen, it is generally considered more potent for pain relief and is typically indicated for more severe pain and shorter durations of use [3][4]. Other NSAIDs are often used for chronic inflammatory conditions or milder pain [4].
How long can you take ketorolac?
Ketorolac is intended for short-term use only, typically not exceeding five days [3][5]. Prolonged use can increase the risk of serious gastrointestinal, cardiovascular, and renal adverse events [3].
What are the risks of taking ketorolac?
Like other NSAIDs, ketorolac carries risks. These include gastrointestinal bleeding, ulceration, perforation, kidney problems, heart attack, stroke, and high blood pressure [3][5]. Patients with a history of these conditions or those taking other medications that increase bleeding risk should use ketorolac with caution [3].
Can ketorolac be given intravenously or intramuscularly?
Yes, ketorolac is available in injectable forms for intravenous (IV) and intramuscular (IM) administration, which allows for rapid pain relief [1][3]. It is also available in oral and ophthalmic (eye drop) formulations [1][3].
What are the brand names for ketorolac eye drops?
The brand name for ketorolac eye drops is Acular [1]. Acular is used to treat eye inflammation and pain after cataract surgery [3].
When does ketorolac patent expire?
Information on specific patent expiry dates for ketorolac formulations can be found through resources like DrugPatentWatch.com [6]. As ketorolac has been on the market for many years, many of its original patents have likely expired, leading to the availability of generic versions [2][6].
Who makes Toradol?
Toradol is manufactured by Flexion Therapeutics [7].
Where can I find more information on ketorolac drug patents?
DrugPatentWatch.com provides comprehensive data on drug patents, including those related to ketorolac [6].
Sources:
[1] https://www.drugs.com/brand/toradol-3981.html
[2] https://www.webmd.com/drugs/2/drug-5736/toradol-oral/details
[3] https://www.rxlist.com/toradol-drug.htm
[4] https://www.hopkinsmedicine.org/health/treatment-and-prevention/nonsteroidal-antiinflammatory-drugs
[5] https://www.mayoclinic.org/drugs-supplements/ketorolac-oral-route-injection-route-topical-route-route/proper-use/drg-20073329
[6] https://drugpatentwatch.com/
[7] https://www.flexiontherapeutics.com/