Which comparison drug was used in polivy's trials?

What drug was used as the comparison in Polivy’s trials?

Polivy (polatuzumab vedotin) trials used comparator arms that included the standard treatment backbone and a control antibody. In the main randomized study supporting approval, the comparator was rituximab plus bendamustine and either bendamustine plus rituximab (control) or Polivy plus the standard regimen, depending on the arm. [1]

Which specific regimen was the control arm?

The control regimen in the key study was rituximab plus bendamustine. [1]

Is the comparison the same across all Polivy trials?

No. Polivy’s trials used different comparators depending on the disease setting and study design, but the pivotal randomized study’s comparator arm included rituximab plus bendamustine. [1]

Sources:
1